Mutation Analyses of COL7A1 Gene in Three Taiwanese Patients with Severe Recessive Dystrophic Epidermolysis Bullosa

Dystrophic epidermolysis bullosa (DEB) is a hereditary mechanobullous disorder characterized by fragility of the skin and mucous membranes caruso rhodiola caused by abnormal anchoring fibrils.Both dominant and recessive DEB are caused by mutations in COL7A1, the gene encoding type VII collagen, the major component of anchoring fibrils.We performed

read more

Armed conflict and fisheries in the Lake Victoria basin

Civil conflict is the most prevalent form of armed conflict in the world today, but this significant driver of food and income security has been largely missing from studies of fisheries.Fisheries conflict is an example of complex dynamics operating in social-ecological systems.We theorize and document the existence of such a feedback loop between

read more

Case Report: A rare presentation and diagnosis of gingival melanoacanthoma caused by teeth whitening strips: A Case Report [version 2; peer review: 2 approved]

Background: Oral melanoacanthoma is not common.It occurs mostly on the buccal mucosa.Since it happens suddenly and progresses rapidly, it clinically resembles melanoma.Melanoacanthoma occurs in regions susceptible to trauma.The clinical presentation of the lesion is not enough to diagnose it; therefore, tissue biopsy is necessary to exclude maligna

read more